EGFR kinase inhibitor 7 (compound 18i) is an EGFR inhibitor (IC50=42.3 nM) with anticancer activity. EGFR kinase inhibitor 7 has significant in vitro cytotoxicity and apoptosis induction ability. EGFR kinase inhibitor 7 has antiproliferative activity against human colon cancer cell line HCT116 and human non-small cell lung cancer cell line A549, with IC50 values of 4.82 µM and 1.43 µM, respectively[1].
Molecular Weight:
653.45
Formula:
C28H26Cl2FN3O3SSe
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound
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