PBE-AMF is a prodrug that activates H2O2 with anticancer activity. PBE-AMF impedes tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBE-AMF potently and selectively inhibits the proliferation of MDA-MB-231 cells (IC50=6.4 µM) while sparing non-cancerous MCF-10A cells[1].
Molecular Weight:
543.42
Formula:
C30H34BN3O6
Target:
Apoptosis,DNA/RNA Synthesis,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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