S-WJM992 (compound 10ahb) is an antiparasitic agent that inhibits ATPase activity under high [Na+] conditions. S-WJM992 also has significant inhibitory effects on parasites that have developed PfATP4 inhibitor-resistance. S-WJM992 is a potential transmission blocker that effectively inhibits gamete development and prevents parasite transmission to mosquitoes via blood feeding[1].
Molecular Weight:
468.87
Formula:
C22H18ClFN6O3
Target:
Na+/K+ ATPase,Parasite
Application Notes:
MCE Product type: Reference compound
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