Autophagy inducer 5 (compound 21o) is a potent MCF-7 inhibitor (IC50: 2 µM), and a potential breast cancer inhibitor. Autophagy inducer 5 induces cellular autophagy by activating the ROS/JNK signaling pathway, which increases ROS generation and JNK phosphorylation, exerting cytotoxic effects[1].
Molecular Weight:
648.88
Formula:
C41H52N4O3
Target:
Autophagy,JNK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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