BMS-986397 is a cereblon-based CK1alpha (casein kinase 1alpha) molecular glue degrader that can cause rapid apoptosis and cell cycle arrest in TP53 wild-type AML (acute myeloid leukemia) cells. BMS-986397 can be used for the study of AML and HR-MDS (High-Risk Myelodysplastic Syndrome)[1].
Molecular Weight:
480.82
Purity:
99.76
CAS Number:
[2564486-44-6]
Formula:
C21H16ClF3N4O4
Target:
Apoptosis,Casein Kinase,Ligands for E3 Ligase,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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