PLX-4545 is an orally active and selective cereblon-based molecular glue degrader of IKZF2 (zinc finger transcription factor Helios). PLX-4545 can reprogram immunosuppressive regulatory T cells into pro-inflammatory effector T cells, thereby enhancing anti-tumor immune responses[1].
Molecular Weight:
473.56
Purity:
96.76
CAS Number:
[2892065-45-9]
Formula:
C28H31N3O4
Target:
IKZF Family,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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