PF-07328948 is an orally effective BDK (branch chain ketoacid dehydrogenase kinase) inhibitor, with IC50 of 110 nM. PF-07328948 acts as a BCKDH (branch chain ketoacid dehydrogenase) enzyme complex degrader to enhance BCAA (branch chain amino acid) catabolism. PF-07328948 improves metabolic and heart failure end points in rats[1].
Molecular Weight:
356.29
Purity:
99.88
CAS Number:
[2936625-34-0]
Formula:
C16H8F4O3S
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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