BMS-986408 is an orally active inhibitor of DGKalpha and DGKzeta, with IC50 values of 0.0003 µM and 0.002 µM, respectively. BMS-986408 activates intratumoral T cell responses, enhances the priming and expansion of tumor-reactive T cells in tumor-draining lymph nodes, and functions as an immunostimulant. BMS-986408 can be used in the research of tumors[1].
Molecular Weight:
512.57
Purity:
99.35
CAS Number:
[2618418-12-3]
Formula:
C27H31F3N6O
Target:
DGK,Interleukin Related,PERK
Application Notes:
MCE Product type: Reference compound1
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