NLRP3-IN-46 (Compound 3k) activates neuro-immunomodulatory cholinergic anti-inflammatory pathway, and thus inhibits NLRP3 inflammasome activation. NLRP3-IN-46 inhibits Uric acid sodium (HY-B2130A)-induced IL-1beta production in THP-1 cells, and can be used in gouty arthritis research[1].
Molecular Weight:
425.36
Formula:
C23H25BrN2O
Target:
NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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