Claturafenib ( PF-07799933) is an orally active inhibitor of pan-mutant BRAF. Claturafenib inhibits pERK in cells (IC50 value of 1.6 nM in HT29 cells). Claturafenib has anticancer activity against BRAFG469A mutant NSCLC and BRAFK601E mutant melanoma[1].
Molecular Weight:
490.31
Purity:
99.95
CAS Number:
[2754408-94-9]
Formula:
C18H15Cl2F2N5O3S
Target:
PERK,Raf
Application Notes:
MCE Product type: Reference compound
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