NR-11c is a selective and potent p38alpha PROTAC degrader. NR-11c effectively degrades p38alpha in a variety of tumor cells. When administered intraperitoneally or intravenously to mice, NR-11c primarily acts in the liver. NR-11c can be used in cancer research. (Pink: p38alpha inhibitor 5 (HY-159799), Black: linker (HY-159800), Blue: VHL E3 ligase ligand (HY-112078))[1].
Molecular Weight:
1198.22
Purity:
99.75
Formula:
C59H71BrF2N10O8S
Target:
p38 MAPK,PROTACs
Application Notes:
MCE Product type: Reference compound
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