PAR4 antagonist 7 (Compound 20f) is selective PAR4 antagonist (IC50: 1.72 nM). PAR4 antagonist 7 inhibits PAR4 agonist-induced platelet aggregation. PAR4 antagonist 7 has good metabolic stability. PAR4 antagonist 7 does not show a bleeding tendency in mice[1].
Molecular Weight:
541.55
Formula:
C28H20FN5O4S
Target:
Protease Activated Receptor (PAR)
Application Notes:
MCE Product type: Reference compound
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