HW161023 (compound 5) is an orally active AP2-associated protein kinase 1 (AAK1) inhibitor with IC50 values of 5.4 nM and 11.9 µM aganist of AAK1and hERG, respectively. HW161023 inhibits the pain in chronic constriction injury of the sciatic nerve rat model[1].
Molecular Weight:
374.43
CAS Number:
[2920698-73-1]
Formula:
C20H24F2N4O
Target:
AAK1
Application Notes:
MCE Product type: Reference compound1
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