LMP517 (NSC 781517) is a potent and non-camptothecin Topoisomerase I and II (TOP1 and TOP2) dual inhibitor. LMP517 can induce TOP1 and TOP2 cleavage complexes (TOP1ccs and TOP2ccs). LMP517 can induce cancer cells DNA damage and gammaH2AX production. LMP517 can be used for the research of cancer, such as small cell lung cancer[1][2].
Molecular Weight:
410.40
Purity:
99.58
CAS Number:
[1883730-99-1]
Formula:
C22H19FN2O5
Target:
DNA/RNA Synthesis,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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