Gint4.T aptamer (sodium) Preis auf Anfrage

Catalog Number: MCE-HY-160053
Article Name: Gint4.T aptamer (sodium) Preis auf Anfrage
Biozol Catalog Number: MCE-HY-160053
Supplier Catalog Number: HY-160053
Alternative Catalog Number: MCE-HY-160053-1UNIT
Manufacturer: MedchemExpress
Category: Sonstiges
Gint4.T aptamer sodium is a nuclease-resistant RNA aptamer-based antagonist targeting platelet-derived growth factor receptor beta (PDGFRbeta) (Kd: 9.6 nM). Gint4.T aptamer sodium inhibits PDGFRbeta heterodimerization and EGFR transactivation. It can significantly inhibit cell migration and proliferation, induce differentiation and prevent tumor growth in vivo. Gint4.T aptamer sodium specifically inhibits PDGFRbeta-mediated tropism of mesenchymal stem cells (MSCs) toward the tumor microenvironment[1].
Target: PDGFR
Application Notes: MCE Product type: Oligonucleotides