20-5,14-HEDE (WIT003) is an analog of 20-HETE. 20-5,14-HEDE activates PI3K/Akt signaling pathway, thereby exhibiting anti-apoptotic and cell survival promoting effects. 20-5,14-HEDE is the agonist for 20-HETE that increases intracellular Ca2+ concentrations, thereby enhancing vasoconstriction[1][2].
Molecular Weight:
324.50
Purity:
98.34
CAS Number:
[240427-86-5]
Formula:
C20H36O3
Target:
Akt,Apoptosis,Caspase,DNA/RNA Synthesis,PI3K,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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