TDP-43 degrader-1 (Compound example 7) is a TDP-43 degrader. TDP-43 degrader-1 reduces the aggregation of TDP-43-positive HuR stress granules in cells and promotes the relocalization of abnormally distributed TDP-43 in the cytoplasm to the nucleus. TDP-43 degrader-1 can be used in the study of amyotrophic lateral sclerosis and Alzheimers disease[1].
Molecular Weight:
455.55
Purity:
95.00
CAS Number:
[2902692-25-3]
Formula:
C28H29N3O3
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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