(R,R)-Birelentinib, CAS [[2662512-14-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-160167A
Supplier Catalog Number:
HY-160167A
Alternative Catalog Number:
MCE-HY-160167A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
(R,R)-DZD8586
(R,R)-Birelentinib (Compound 14) is a potent BTK inhibitor with IC50 values for BTK WT and BTK C481S of 0.7 and 0.86 nM, respectively. (R,R)-Birelentinib inhibits the self-phosphorylation of BTK and its IC50 is 24.3 nM. (R,R)-Birelentinib exhibits significant anti-proliferative activity against wild-type and C481S mutant HEK293 cells. (R,R)-Birelentinib can be used for the study of drug-resistant B-cell malignancies[1].
Molecular Weight:
453.45
CAS Number:
[2662512-14-1]
Formula:
C23H21F2N5O3
Target:
Btk
Application Notes:
MCE Product type: Reference compound
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