Ilorasertib (ABT-348) hydrochloride is a potent, orally active and ATP-competitive aurora inhibitor with IC50s of116, 5, 1 nM for aurora A, aurora B, aurora C, respectively. Ilorasertib hydrochloride also is a potent VEGF, PDGF inhibitor. Ilorasertib hydrochloride has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[1][2].
Molecular Weight:
525.00
Purity:
98.48
CAS Number:
[1847485-91-9]
Formula:
C25H22ClFN6O2S
Target:
Aurora Kinase,PDGFR,VEGFR
Application Notes:
MCE Product type: Reference compound
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