DC-SX029 is a potent SNX10 protein-protein interaction (PPI) inhibitor with oral activity with an estimated KD constant of ~0.935 µM by surface plasmon resonance (SPR). DC-SX029 blocks the SNX10-PIKfyve interaction, thereby decreased the TBK1/c-Rel signaling activation. DC-SX029 does not affect the protein level of SNX10. DC-SX029 has the potential for inflammatory bowel disease (IBD) research[1][2].
Molecular Weight:
398.35
Purity:
98.07
CAS Number:
[300713-88-6]
Formula:
C14H17F3N2O6S
Target:
IKK,NF-kappaB,PIKfyve
Application Notes:
Reference compound
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