LXQ46 is an orally active inhibitor for protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 0.190 µM. LXQ46 enhances insulin and leptin signaling pathways in insulin-resistant C2C12. LXQ46 ameliorates type 2 diabetes and increases insulin tolerance in mouse models[1].
Molecular Weight:
547.19
CAS Number:
[2097148-94-0]
Formula:
C23H17Br2NO5
Target:
Phosphatase
Application Notes:
Reference compound
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