PLK1/BRD4-IN-3 (Compound 21) is a selective dual inhibitor for bromodomain 4 (BRD4) and polo-like kinase 1 (PLK1). PLK1/BRD4-IN-3 inhibits BRD4-BD1, PLK1 and BRDT-BD1, with IC50s of 0.059, 0.127 and 0.245 µM, respectively[1].
Molecular Weight:
561.72
Purity:
99.66
CAS Number:
[2251709-91-6]
Formula:
C31H43N7O3
Target:
Epigenetic Reader Domain,Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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