GW814408X is a kinase chemical genome group (KCGS) compound that inhibits the AURKC kinase involved in cell cycle progression, checkpoint regulation, and cell division. GW814408X exhibits cell line-dependent toxicity, e.g., cytotoxic effects on HeLa cells. GW814408X acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].
Molecular Weight:
344.37
CAS Number:
[886599-05-9]
Formula:
C19H16N6O
Target:
Aurora Kinase
Application Notes:
MCE Product type: Reference compound
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