VNPP433-3beta (dihydrochloride), CAS [[3026905-92-7]] Preis auf Anfrage

Catalog Number: MCE-HY-160777A
Article Name: VNPP433-3beta (dihydrochloride), CAS [[3026905-92-7]] Preis auf Anfrage
Biozol Catalog Number: MCE-HY-160777A
Supplier Catalog Number: HY-160777A
Alternative Catalog Number: MCE-HY-160777A-1UNIT
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: Galeterone 3beta-imidazole (dihydrochloride)
VNPP433-3beta (Galeterone 3beta-imidazole) dihydrochloride is an orally active molecular glue degrader, which degrades androgen receptor (AR) and its splice variants (AR-Vs) and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. VNPP433-3beta dihydrochloride induces cell apoptosis. VNPP433-3beta dihydrochloride inhibits tumor growth in the CWR22Rv1 xenograft mouse model. VNPP433-3beta dihydrochloride can be used for the study of castration resistant prostate cancer (CRPC) and pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight: 511.53
CAS Number: [3026905-92-7]
Formula: C29H36Cl2N4
Target: Androgen Receptor,Apoptosis,MNK,Molecular Glues
Application Notes: MCE Product type: Reference compound