VNPP433-3beta (dihydrochloride), CAS [[3026905-92-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-160777A
Supplier Catalog Number:
HY-160777A
Alternative Catalog Number:
MCE-HY-160777A-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Galeterone 3beta-imidazole (dihydrochloride)
VNPP433-3beta (Galeterone 3beta-imidazole) dihydrochloride is an orally active molecular glue degrader, which degrades androgen receptor (AR) and its splice variants (AR-Vs) and MAP kinase-interacting serine/threonine protein kinase Mnk1/2. VNPP433-3beta dihydrochloride induces cell apoptosis. VNPP433-3beta dihydrochloride inhibits tumor growth in the CWR22Rv1 xenograft mouse model. VNPP433-3beta dihydrochloride can be used for the study of castration resistant prostate cancer (CRPC) and pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight:
511.53
CAS Number:
[3026905-92-7]
Formula:
C29H36Cl2N4
Target:
Androgen Receptor,Apoptosis,MNK,Molecular Glues
Application Notes:
MCE Product type: Reference compound
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