O-Desmethyl dacomitinib, CAS [[2468202-15-3]] Preis auf Anfrage

Product Overview

• Article Name: O-Desmethyl dacomitinib, CAS [[2468202-15-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-160828
• Supplier Catalog Number: HY-160828
• Alternative Catalog Number: MCE-HY-160828-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PF-05199265

Product Description

O-Desmethyl dacomitinib (PF-05199265) is the major circulating metabolite of dacomitinib (HY-13272) and acts as a pan-epidermal growth factor receptor (ErbB) tyrosine kinase inhibitor. O-Desmethyl dacomitinib exhibits a much lower exposure level than dacomitinib in the body. O-Desmethyl dacomitinib is highly dependent on the enzymatic activity of CYP2D6 for its formation[1].

Product Properties

• Molecular Weight: 455.91
• CAS Number: [2468202-15-3]
• Formula: C23H23ClFN5O2
• Target: Drug Metabolite,EGFR

Application Notes

• Application Notes: MCE Product type: Reference compound