PQQ-trimethylester (PQQ-TME) is a synthetic compound that is a trimethylester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimethylester has twice the blood-brain barrier permeability of PQQ (HY-100196) in vitro. In addition, PQQ-trimethylester shows strong inhibitory activity against alpha-synuclein, amyloid beta1-42 (Abeta1-42) and prion protein fibrillation. PQQ-trimethylester can be used in the study of neurodegenerative diseases[1].
Molecular Weight:
372.29
Purity:
95
CAS Number:
[74447-88-4]
Formula:
C17H12N2O8
Target:
alpha-synuclein
Application Notes:
MCE Product type: Reference compound
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