FPT, a 2-Aminotetralin, is an efficacious partial agonist at 5-HT1AR, a full agonist at 5-HT1BR and 5-HT1DR with EC50s of 39.3 nM, 1.2 nM, 0.5 nM, respectively. FPT is a weak agonist at 5-HT7R. FPT shows in vivo efficacy as an antiepileptic in Fmr1 knockout mice and has anxiolytic-like and prosocial effects in Fmr1 knockout mice and other mouse models[1].
Molecular Weight:
269.36
Purity:
98.06
CAS Number:
[2048491-06-9]
Formula:
C18H20FN
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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