HPK1-IN-46, CAS [[2810880-82-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-160940
Supplier Catalog Number:
HY-160940
Alternative Catalog Number:
MCE-HY-160940-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
HPK1-IN-46 (Compound 36) is an efficient and highly selective HPK1 reverse indazole inhibitor with an IC50 value of 1.1 nM. HPK1-IN-46 exhibits high selectivity for CDK2, JAK1, and JAK2. HPK1-IN-46 inhibits SLP76 phosphorylation mediated by HPK1, reverses T-cell inhibition, and enhances anti-tumor immunity. HPK1-IN-46 can be used in immunotherapy research for tumors[1].
Molecular Weight:
444.50
CAS Number:
[2810880-82-9]
Formula:
C25H25FN6O
Target:
MAP4K
Application Notes:
MCE Product type: Reference compound
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