PROTAC Chk1 degrader-1 is a Chk1-targeting PROTAC.PROTAC Chk1 degrader-1 recruits the Cereblon E3 ligase to induce ubiquitination and proteasomal degradation of Chk1.PROTAC Chk1 degrader-1 exhibits Chk1 degradation activity in malignant melanoma cells without showing a hook effect.PROTAC Chk1 degrader-1 can be used for the research of malignant melanoma[1].
Molecular Weight:
900.90
Purity:
99.70
CAS Number:
[2597167-34-3]
Formula:
C43H44N14O9
Target:
Checkpoint Kinase (Chk),PROTACs
Application Notes:
MCE Product type: Reference compound
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