BTX-6654 is a target-dependent and -specific cereblon-based bifunctional SOS1 PROTAC degrader. BTX-6654 reduces downstream signaling markers pERK and pS6, and displays antiproliferative activity in cells harboring various KRAS mutations[1].
Molecular Weight:
940.04
Formula:
C50H57F4N9O5
Target:
ERK,PROTACs,SOS1
Application Notes:
Reference compound
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