KRAS ligand 4 (compound 2) is a bifunctional molecular glue degrader based on SOS1. KRAS ligand 4 reduces downstream signaling markers pERK and pS6 and displays anti-additional activity in cells with multiple KRAS mutations[1].
Molecular Weight:
540.97
Formula:
C24H28ClF3N6O3
Target:
Molecular Glues,Ras,SOS1
Application Notes:
Reference compound
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