Carboxyamidotriazole (L-651582) is an orally active cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways. Carboxyamidotriazole inhibits NF-kappaB, MAPK activation and NO production. Carboxyamidotriazole has anti-angiogenic and anti-inflammatory activities. Carboxyamidotriazole has anticancer activity against liver cancer, lung cancer and leukemia[1][2][3][4][5][6][7][8][9][10][11][12][13].
Molecular Weight:
424.67
Purity:
99.82
CAS Number:
[99519-84-3]
Formula:
C17H12Cl3N5O2
Target:
Calcium Channel,NF-kappaB,NO Synthase,p38 MAPK
Application Notes:
Reference compound
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