P-gp inhibitor 20 (compound H27) is a low cytotoxicity P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 20 inhibits the efflux function of P-gp in a dose-dependent manner (without affecting the expression of P-gp), thereby reversing the multidrug resistance (MDR) of MCF-7/ADR cells, with an IC50 value of 46.6 nM. P-gp inhibitor 20 can be used for cancer research[1].
Molecular Weight:
571.53
Formula:
C30H28N4O3Se
Target:
P-glycoprotein
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
