Poltheta/PARP-IN-1

Product Overview

• Article Name: Poltheta/PARP-IN-1
• Biozol Catalog Number: MCE-HY-161302
• Supplier Catalog Number: HY-161302
• Alternative Catalog Number: MCE-HY-161302-10MG,MCE-HY-161302-5MG,MCE-HY-161302-10MMX1ML,MCE-HY-161302-50MG,MCE-HY-161302-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Poltheta/PARP-IN-1 (compound 25d) is a potent dual DNA polymerase theta (Poltheta) and PARP inhibitor with IC50 values of 45.6, 5.4 nM, respectively. Poltheta/PARP-IN-1 shows antiproliferative activity. Poltheta/PARP-IN-1 induces apoptosis and cell cycle arrest at G2/M phase, causes DNA damage. Poltheta/PARP-IN-1 shows anti-tumor activity[1].

Product Properties

• Molecular Weight: 754.23
• Purity: 99.08
• Formula: C38H33ClFN7O5S
• Target: Apoptosis,DNA/RNA Synthesis,PARP

Application Notes

• Application Notes: Reference compound