SE-7552, a 2-(difluoromethyl)-1,3,4-oxadiazole (DFMO) derivative, is an orally active, highly selective, non-hydroxamate HDAC6 inhibitor with an IC50 of 33 nM. SE-7552 is greater than 850-fold selectivity versus all other known HDAC isozymes. SE-7552 is capable of blocking multiple myeloma growth in vivo. SE-7552 acts as an anti-obesity agent in diet-induced obese mice[1][2].
Molecular Weight:
335.28
Purity:
99.48
CAS Number:
[2243575-79-1]
Formula:
C15H12F3N5O
Target:
HDAC
Application Notes:
Reference compound
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