T-518 is an orally active, BBB-penetrant and potent DFMO-based HDAC6 inhibitor with high selectivity (IC50 = 36 nM). T-518 improves axonal transport. T-518 ameliorates object recognition deficit. T-518 can be studied in research for Alzheimers disease and tauopathy[1][2].
Molecular Weight:
495.35
Purity:
98.40
CAS Number:
[2276680-91-0]
Formula:
C19H16F7N5O3
Target:
HDAC,Microtubule/Tubulin
Application Notes:
Reference compound
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