PTP1B-IN-24 (Compound 9) is a reversible PTP1B inhibitor with an IC50 value of 1.4 µM, and PTP1B-IN-24 can enhance the thermal stability of PTP1B. PTP1B-IN-24 can restore PA- (HY-N0830) induced insulin resistance by increasing the phosphorylation levels of IRS1 and AKT[1].
Molecular Weight:
420.44
Purity:
95.01
CAS Number:
[2221707-61-3]
Formula:
C22H16N2O5S
Target:
Akt,Insulin Receptor,Phosphatase
Application Notes:
Reference compound
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