VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. VD4162 can significantly improve potency for all four target enzymes TMPRSS2 (IC50 = 3.7 nM), HGFA(IC50 = 3.3 nM), matriptase (IC50 = 2.9 nM), and hepsin (IC50 = 0.54 nM). VD4162 can be used for the research of cancer[1].
Molecular Weight:
793.93
CAS Number:
[2574390-19-3]
Formula:
C41H47N9O6S
Target:
Ser/Thr Protease
Application Notes:
Reference compound
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