M4K2281 is a selecitve inhibitor for activin receptor-like kinase-2 (ALK2) with an IC50 of 2 nM. M4K2281 exhibits a moderate blood brain permeability with a brain to plasma ratio of 3.7 at 4h[1].
Molecular Weight:
461.55
Formula:
C27H31N3O4
Target:
TGF-beta Receptor
Application Notes:
Reference compound
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