Ivaltinostat, CAS [[936221-33-9]] Preis auf Anfrage

Product Overview

• Article Name: Ivaltinostat, CAS [[936221-33-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-16138
• Supplier Catalog Number: HY-16138
• Alternative Catalog Number: MCE-HY-16138-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: CG-200745

Product Description

Ivaltinostat (CG-200745) is an orally active, potent pan-HDAC inhibitor which has the hydroxamic acid moiety to bind zinc at the bottom of catalytic pocket. Ivaltinostat inhibits deacetylation of histone H3 and tubulin. Ivaltinostat induces the accumulation of p53, promotes p53-dependent transactivation, and enhances the expression of MDM2 and p21 (Waf1/Cip1) proteins. Ivaltinostat enhances the sensitivity of Gemcitabine-resistant cells to Gemcitabine (HY-16138) and 5-Fluorouracil (5-FU, HY-90006). Ivaltinostat induces apoptosis and has anti-tumour effects[1][2][3][4].

Product Properties

• Molecular Weight: 427.54
• CAS Number: [936221-33-9]
• Formula: C24H33N3O4
• Target: Apoptosis,HDAC,MDM-2/p53

Application Notes

• Application Notes: MCE Product type: Reference compound