CHK1-IN-9 (compound 11) is an orally active CHK1 inhibitor with an IC50 value of 0.55 nM. CHK1-IN-9 can enhance the effect of DNA-damaging drugs on tumor cells. CHK1-IN-9 has synergistic anticancer effects with Gemcitabine (HY-17026)[1].
Molecular Weight:
412.40
Formula:
C19H18F2N8O
Target:
Checkpoint Kinase (Chk)
Application Notes:
MCE Product type: Reference compound
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