Topoisomerase I inhibitor 21 (Compound 3e) is an inhibitor for Topoisomerase I through stabilization of enzyme-DNA complex. Topoisomerase I inhibitor 21 exhibits antiproliferative activity in 39 human cancer cells (JFCR39) with mean GI50 39 nM[1].
Molecular Weight:
457.52
Formula:
C27H27N3O4
Target:
Topoisomerase
Application Notes:
MCE Product type: Reference compound
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