SC912 is an AR-V7 inhibitor (IC50 = 0.36 µM). SC912 possesses safety, potency and selectivity. SC912 binds directly to AR-FL and AR-V7 proteins, inhibites nuclear localization and chromatin binding capabilities. SC912 exerts anticancer activity through inhibition of proliferation, induction of cell cycle arrest and apoptosis[1].
Molecular Weight:
493.27
Purity:
99.13
Formula:
C22H13Cl2F3N4O2
Target:
Androgen Receptor,Apoptosis
Application Notes:
Reference compound
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