RTx-152, CAS [[3035072-48-8]]

Catalog Number: MCE-HY-161431
Article Name: RTx-152, CAS [[3035072-48-8]]
Biozol Catalog Number: MCE-HY-161431
Supplier Catalog Number: HY-161431
Alternative Catalog Number: MCE-HY-161431-5MG,MCE-HY-161431-10MG,MCE-HY-161431-50MG,MCE-HY-161431-25MG
Manufacturer: MedchemExpress
Category: Biochemikalien
RTx-152 traps Poltheta on DNA and is an allosteric Poltheta-pol inhibitor (IC50: 6.2 nM). RTx-152 selectively kills HR-deficient cancer cells, and suppresses PARP inhibitor resistance in multiple genetic backgrounds, including homologous recombination (HR)-proficient cells. RTx-152 selectively kills BRCA2-null cells[1].
Molecular Weight: 479.35
Purity: 99.71
CAS Number: [3035072-48-8]
Formula: C20H16F7N3O3
Target: DNA/RNA Synthesis
Application Notes: Reference compound