SIK-IN-1, CAS [[3033846-29-3]]

Product Overview

• Article Name: SIK-IN-1, CAS [[3033846-29-3]]
• Biozol Catalog Number: MCE-HY-161440
• Supplier Catalog Number: HY-161440
• Alternative Catalog Number: MCE-HY-161440-25MG,MCE-HY-161440-10MG,MCE-HY-161440-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SIK-IN-1 (Compound 53) is an inhibitor for salt-inducible kinase (SIK), which inhibits SIK1, SIK2 and SIK3 with IC50s of 0.1, 0.4 and 1.5 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC50 of 0.5 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC50 of 4 nM in human macrophages[1].

Product Properties

• Molecular Weight: 432.54
• Purity: 98.91
• CAS Number: [3033846-29-3]
• Formula: C23H24N6OS
• Target: AMPK

Application Notes

• Application Notes: Reference compound