TEAD-IN-9 (compound 17) is a TEAD1 inhibitor with an IC50 of 0.29 µM. TEAD-IN-9 targets the palmitoyl pocket of TEAD, thereby effectively inhibiting the binding of YAP-TEAD and blocking the transcriptional function of YAP-TEAD[1].
Molecular Weight:
477.42
Formula:
C23H23F3N3O3P
Target:
YAP
Application Notes:
Reference compound
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