AChE-IN-62 (Compound 1) is an effective mixed and selective acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.421 µM. AChE-IN-62 exhibits excellent blood-brain barrier permeability and neuroprotective effects. Additionally, AChE-IN-62 can inhibit the aggregation of Abeta1-42 with an IC50 value of 44.64 µM. AChE-IN-62 is also an effective multi-target-directed ligand (MTDL) that can be utilized in the research of Alzheimers disease[1].
Molecular Weight:
431.53
Formula:
C19H21N5O3S2
Target:
Amyloid-beta,Cholinesterase (ChE)
Application Notes:
MCE Product type: Reference compound
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