Anemoside A3-methyl 6-aminohexanoate (Compound A3-6) is a derivative of Pulchinenoside C (Anemoside B4) (HY-N0205). Anemoside A3-methyl 6-aminohexanoate inhibits pyruvate carboxylase (PC) with an IC50 of 0.058 µM, reprograms macrophage function, and alleviates DSS-induced colitis through inhibition of the NF-kappaB and NLRP3 inflammasome pathway. Anemoside A3-methyl 6-aminohexanoate exhibits a moderate in vivo pharmacokinetic characters compared with Anemoside B4[1].
Molecular Weight:
878.14
Purity:
98.62
CAS Number:
[2919975-48-5]
Formula:
C48H79NO13
Target:
NF-kappaB
Application Notes:
MCE Product type: Reference compound
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