PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.
Molecular Weight:
991.61
Purity:
99.20
CAS Number:
[3034244-71-5]
Formula:
C49H64ClFN10O7S
Target:
EGFR,FAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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