DNMT1-IN-3, CAS [[3025012-68-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-161694
Supplier Catalog Number:
HY-161694
Alternative Catalog Number:
MCE-HY-161694-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DNMT1-IN-3 (compound 7t-S) is an effective DNA methyltransferase 1 (DNMT1) inhibitor with an IC50 value of 0.777 µM and a KD value of 0.183 µM. DNMT1-IN-3 can bind to the methyl donor S-adenosyl-l-methionine (SAM) site in DNMT1. DNMT1-IN-3 can inhibit cell proliferation in K562 cells by inducing cells apoptosis and arresting cell cycle at G0 / G1 phase, which has the potential to be used for the research of hematologic tumor[1].
Molecular Weight:
487.72
CAS Number:
[3025012-68-1]
Formula:
C23H13Cl3N2O4
Target:
DNA Methyltransferase
Application Notes:
MCE Product type: Reference compound1
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